Does corpus luteum locally affect follicular growth negatively?
| Autor: | A.G. Byskov, C. Yding Andersen, Kiyomi Fukuda, Misao Fukuda |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
endocrine system medicine.medical_specialty Time Factors media_common.quotation_subject Ovary Luteal Phase Biology Luteal phase Ovarian Follicle Corpus Luteum Internal medicine Follicular phase medicine Humans Ovarian follicle Ovulation reproductive and urinary physiology Luteal support Menstrual cycle Ultrasonography media_common urogenital system Rehabilitation Obstetrics and Gynecology medicine.anatomical_structure Endocrinology Reproductive Medicine Female Corpus luteum hormones hormone substitutes and hormone antagonists |
| Zdroj: | Human Reproduction. 12:1024-1027 |
| ISSN: | 1460-2350 0268-1161 |
| Popis: | In this study bilateral ovarian follicular growth during the luteal phase was investigated in relation to the ovary where ovulation occurred. The diameter of the largest follicle in the contralateral ovary without corpus luteum and in the ipsilateral ovary with corpus luteum was measured using vaginosonography in a total of 66 natural cycles of 27 normally cycling women undergoing treatment with intrauterine insemination (IUI). None of the women received ovarian stimulation or luteal support. Follicles from 2 to 11 mm in diameter were measured in early luteal phase (day +1 to +4), mid-luteal phase (day +5 to +9) and late luteal phase (day +10 onwards). The mean diameters of the largest follicle in the contralateral ovary without corpus luteum during the early, mid- and late luteal phases were 6.81 +/- 1.33 (mean +/- SD), 6.14 +/- 1.29 and 5.71 +/- 1.17 mm respectively, while those of the ipsilateral ovary with corpus luteum were 6.48 +/- 1.40, 5.65 +/- 1.47 and 4.98 +/- 1.19 mm respectively. While there was no significant difference during the early luteal phase, the mean diameter of the largest follicle in the ipsilateral ovary with corpus luteum was significantly smaller than that of the contralateral ovary without corpus luteum during the mid-luteal phase (P < 0.004) and the late luteal phase (P < 0.0005). These results indicate that the corpus luteum locally affects neighbouring follicular growth negatively during the luteal phase of the menstrual cycle, with the most pronounced effect expressed in the mid- and late luteal phases. |
| Databáze: | OpenAIRE |
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