| Autor: |
Pooja Pandey, Kimaya Meher, Berness Falcao, Manu Lopus, V. L. Sirisha |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. |
| ISSN: |
1432-1327 |
| Popis: |
Several microbial pathogens are capable of forming biofilms. These microbial communities pose a serious challenge to the healthcare sector as they are quite difficult to combat. Given the challenges associated with the antibiotic-based management of biofilms, the research focus has now been shifted towards finding alternate treatment strategies that can replace or complement the antibacterial properties of antibiotics. The field of nanotechnology offers several novel and revolutionary approaches to eradicate biofilm-forming microbes. In this study, we evaluated the antibacterial and antibiofilm efficacy of in-house synthesized, tryptone-stabilized silver nanoparticles (Ts-AgNPs) against the superbug Serratia marcescens. The nanoparticles were of spherical morphology with an average hydrodynamic diameter of 170 nm and considerable colloidal stability with a Zeta potential of - 24 ± 6.15 mV. Ts-AgNPs showed strong antibacterial activities with a minimum inhibitory concentration (MIC |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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