Preoperative oral health care reduces postoperative inflammation and complications in oral cancer patients
| Autor: | Kouji Ohta, Shinichi Fujimoto, Yoko Ishida, Takayuki Nakagawa, Akiko Fukui, Megumi Takamoto, Hiroshi Shimasue, Toshiya Okumura, Gaku Okui, Sayaka Seino, Masaru Sugiyama, Yoshiaki Ninomiya, Takako Naruse, Mohammad Zeshaan Rahman, Tomoko Tokikazu, Miho Hashikata, Akiko Nimiya, Ryo Uetsuki, Shigehiro Ono, Hideo Shigeishi, Misato Tada, Kuniko Mizuta, Kazuki Sasaki, Masaaki Takechi, Kazumi Kubozono, Koichiro Higashikawa, Kazuhiro Yamamoto, Hiromi Nishi, Kana Dainobu, Fumi Ishida |
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| Rok vydání: | 2016 |
| Předmět: |
Cancer Research
medicine.medical_specialty business.industry Cancer Retrospective cohort study Articles 030206 dentistry General Medicine Anastomosis medicine.disease Surgery stomatognathic diseases 03 medical and health sciences Pneumonia 0302 clinical medicine medicine.anatomical_structure Immunology and Microbiology (miscellaneous) 030220 oncology & carcinogenesis White blood cell medicine Oral health care Stage (cooking) Postoperative inflammation business |
| Zdroj: | Experimental and Therapeutic Medicine. 12:1922-1928 |
| ISSN: | 1792-1015 1792-0981 |
| Popis: | The records of 70 patients with oral cancer who were treated at a single institution between 2008 and 2014 were reviewed. The body temperature, white blood cell count, and C-reactive protein (CRP) levels were compared between those who had received preoperative oral care (oral care group) and those who had not received any (non-oral care group). When the patients were divided into those who underwent minimally invasive surgery and those who underwent severely invasive surgery, the mean CRP level in the early postoperative period was lower in the oral care group as compared with the non-oral care group in those who underwent minimally invasive surgery as well as those who underwent severely invasive surgery. However, the mean CRP level was most evidently reduced in the severely invasive group on days 1 and 3–5. However, no significant differences were observed with regard to the percentage of postoperative infectious complications (for example, surgical site infection, anastomotic leak and pneumonia) between the oral care (13.6%) and non-oral care (20.8%) groups, though a reduced prevalence of postoperative complications following preoperative oral care was noted. The results of the present study suggest that preoperative oral care can decrease inflammation during the early postoperative stage in patients with oral cancer who undergo severely invasive surgery. |
| Databáze: | OpenAIRE |
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