Neuropsychological outcomes after pulmonary endarterectomy using moderate hypothermia and periodic circulatory arrest
| Autor: | Antonio Sciortino, Benedetta Vanini, Maurizio Pin, Catherine Klersy, Vera N. Merli, Pierluigi Politi, Anna Celentano, Lucia Petrucci, Maurizio Salati, Andrea Maria D'Armini, Valentina Grazioli, Ilaria Parisi |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Time Factors Adolescent Hypertension Pulmonary Endarterectomy Neuropsychological Tests Pulmonary Artery 030204 cardiovascular system & hematology Pulmonary endarterectomy Young Adult 03 medical and health sciences 0302 clinical medicine Quality of life Hypothermia Induced Thromboembolism Internal medicine Humans Medicine Prospective Studies Depression (differential diagnoses) Aged Aged 80 and over Transplantation business.industry Neuropsychology Middle Aged Combined Modality Therapy Treatment Outcome 030228 respiratory system Moderate hypothermia Circulatory system Heart Arrest Induced Cardiology Anxiety Female Surgery Observational study medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | The Journal of Heart and Lung Transplantation. 37:860-864 |
| ISSN: | 1053-2498 |
| Popis: | Background In this prospective, single-center, observational study, we investigated the association between repeated short periods of circulatory arrest with moderate hypothermia during pulmonary endarterectomy (PEA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and different neuropsychological dimensions. Methods We examined 70 patients with CTEPH, >18 to 80 years of age, who had been treated with PEA. Neuropsychological testing was performed. Results Learning ability and delayed memory remained well within the normal range for patients’ age. We found a statistically significant post-surgical improvement in motor speed, which was accompanied by a better quality of life and reduced symptoms of depression and anxiety. Conclusion PEA with repeated short periods of circulatory arrest in CTEPH did not result in any neuropsychological complications and may even lead to post-surgical psychological improvements. |
| Databáze: | OpenAIRE |
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