Startling hyperglycaemia with transient beta cell stunning in a patient with type 2 diabetes
| Autor: | Masaki Kakizawa, Toru Aizawa, Yuka Sato, Masayuki Takayama, Takahide Miyamoto, Shin-Ichi Aso, Koh Yamashita |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment 030209 endocrinology & metabolism Type 2 diabetes 03 medical and health sciences 0302 clinical medicine Endocrinology Insulin-Secreting Cells Diabetes mellitus Internal medicine Insulin Secretion medicine Humans Hypoglycemic Agents Insulin Outpatient clinic Gliclazide Diabetic Coma Glycated Hemoglobin Osmole C-Peptide business.industry Insulin glargine Ketosis Middle Aged medicine.disease Diabetes Mellitus Type 2 Pancreatitis Hyperglycemia 030220 oncology & carcinogenesis Regular insulin Fluid Therapy Acidosis Lactic Female business medicine.drug |
| Zdroj: | Endocrine Journal. 67:95-98 |
| ISSN: | 1348-4540 0918-8959 |
| Popis: | A 59-year-old woman unaware of having diabetes was transferred due to coma. Upon discovery at home, her consciousness on the Glasgow Coma Scale was E1V2M4, BP 95/84 mmHg, body temperature 34.7°C. On arrival at ER, height was 1.63 m, weight 97 kg, plasma glucose (PG) 1,897 mg/dL, HbA1c 13.6%, osmolality 421 mosm/kg, arterial pH 7.185, lactate 6.34 mmol/L, β-hydroxybutyrate 7.93 mmol/L. With saline and regular insulin infusion, PG was lowered to 1,440 mg/dL at 2 hours and then to 250 mg/dL by Day 3, and consciousness normalized by Day 5. On admission, serum immunoreactive insulin (IRI) was undetectable ( |
| Databáze: | OpenAIRE |
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