The diagnostic and prognostic value of nuclear matrix protein 22 in bladder cancer

Autor:	Jia Liu, Yong Yang, Yudong Cao, Peng Du, Xingxing Tang, Shuo Wang
Rok vydání:	2020
Předmět:	Cancer Research Bladder cancer business.industry oncology outcomes medicine.disease Nuclear matrix Oncology Cancer research medicine bladder cancer pathologic features Original Article Nuclear matrix protein 22 (NMP22) Radiology Nuclear Medicine and imaging business Value (mathematics)
Zdroj:	Translational Cancer Research
ISSN:	2219-6803 2218-676X
Popis:	Backgrounds This study aimed to evaluate the diagnostic and prognostic value of urine nuclear matrix protein 22 (NMP22) for bladder cancer. Methods A retrospective analysis was performed on 229 patients with bladder cancer who underwent transurethral resection of bladder tumor between 2015 and 2018 in our hospital. The sensitivity of NMP22 was calculated to evaluate the diagnostic value of NMP22. Logistic regression analyses were applied to investigate the prognostic value of NMP22 for pathologic features in bladder cancer. Results The sensitivity of NMP22 for the detection of bladder cancer was 28.82%, and the false negative rate was 71.18%. The sensitivity of NMP22 for the detection of low-grade disease and high-grade disease were 11.11% and 38.51%. NMP22 had significantly higher sensitivity for the detection of high-grade bladder cancer (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f2ba261057bfc722d03a6edf6b0cdf https://doi.org/10.21037/tcr-20-1824 Zobrazit plný text záznamu