The prevalence and clinical significance of intestinal parasites in HIV-infected patients in Denmark
| Autor: | Susanne Dam Nielsen, Jørgen Engberg, Jens-Henrik Badsberg, Christen Rune Stensvold, Alice Friis-Møller, Nina Friis-Møller, Henrik Vedel Nielsen, Sanne Søgaard Nielsen |
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| Rok vydání: | 2010 |
| Předmět: |
Diarrhea
Male Microbiology (medical) medicine.medical_specialty Denmark HIV Infections Polymerase Chain Reaction Gastroenterology Men who have sex with men Feces Acquired immunodeficiency syndrome (AIDS) Immunopathology Internal medicine parasitic diseases Prevalence medicine Animals Humans Parasites Clinical significance Intestinal Diseases Parasitic Sida Microscopy Bacteria General Immunology and Microbiology biology Cryptosporidium Bacterial Infections General Medicine medicine.disease biology.organism_classification Gastroenteritis Isospora Infectious Diseases Immunology Female Viral disease |
| Zdroj: | Scandinavian Journal of Infectious Diseases. 43:129-135 |
| ISSN: | 1651-1980 0036-5548 |
| Popis: | To investigate the prevalence and clinical significance of intestinal parasites in human immunodeficiency virus (HIV)-infected patients, faecal specimens from 96 HIV-infected patients were submitted to microbiological analyses, including microscopy and polymerase chain reaction for protozoa and enteropathogenic bacteria. Results of microbiological analyses were compared with self-reported gastrointestinal complaints collected using a validated questionnaire. Thirty-two (33%) patients were positive for parasites. However, opportunistic parasites (Isospora and Cryptosporidium) were detected in only 2 instances. Entamoeba dispar was detected in 10 cases, 9 of which represented men who have sex with men (MSM). Despite generally low HIV RNA loads and high CD4+ T-cell counts, 42% of the 76 patients reporting symptoms complained of diarrhoea, 31% of whom were parasite-positive. The presence of diarrhoea was not associated with the presence or absence of parasites; neither was it associated with receiving highly active anti-retroviral therapy (HAART) in general, or protease inhibitors (PI) in particular. A CD4+ T-cell count |
| Databáze: | OpenAIRE |
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