Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population
Autor: | Patti E. Gravitt, Yin Ling Woo, Nirmala Bhoo-Pathy, Pik Pin Goh, Su Pei Khoo, Shridevi Subramaniam, Zhang Lin, Jerome L. Belinson, Xinfeng Qu, Mohd Khairul Anwar Shafii, Siew Hwei Yap, Nazrila Hairizan Nasir |
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Rok vydání: | 2021 |
Předmět: |
Male
Viral Diseases Epidemiology Anal Canal Pathology and Laboratory Medicine Human Papillomavirus DNA Tests Men who have sex with men Geographical Locations Medical Conditions Genotype Ethnicity Prevalence Medicine and Health Sciences Multidisciplinary Human papillomavirus 11 Cancer Risk Factors HPV infection virus diseases Middle Aged Anal canal female genital diseases and pregnancy complications Infectious Diseases medicine.anatomical_structure Oncology Medical Microbiology Viral Pathogens Viruses Medicine Independent Living Pathogens Research Article Adult Human Papillomavirus Infection medicine.medical_specialty Asia Adolescent Papillomaviruses Urology Science Sexually Transmitted Diseases Men WHO Have Sex with Men Genitalia Male HPV-18 Microbiology medicine Humans Sex organ Microbial Pathogens Genotyping Biology and life sciences Genitourinary Infections business.industry Public health Papillomavirus Infections Malaysia Organisms Human Papillomavirus Human papillomavirus 6 medicine.disease Carriage Socioeconomic Factors Medical Risk Factors People and Places Population Groupings DNA viruses business Sexuality Groupings Demography |
Zdroj: | PLoS ONE, Vol 16, Iss 1, p e0245731 (2021) PLoS ONE |
ISSN: | 1932-6203 |
Popis: | Background Addressing the burden of HPV-associated diseases among men is increasingly becoming a public health issue. The main objective of this study was to determine HPV prevalence among a healthy community-based Malaysian men. Method This was a cross-sectional study that recruited 503 healthy males from 3 community-based clinics in Selangor, Malaysia. Genital and anal samples were collected from each participant for 14 high risk and 2 low risk HPV DNA detection and genotyping. All participants responded to a set of detailed sociodemographic and sexual behaviour questionnaire. Results The median age at enrolment was 40 years old (IQR: 31–50). The anogenital HPV6/11 prevalence was 3.2% whereas high risk HPV prevalence was 27.1%. The genital HPV prevalence for HPV6/11 was 2.9% while high risk HPV was 18.8%. HPV6/11 prevalence in the anal canal was 1.6% and high risk HPV was 12.7%. HPV 18 was the most prevalent genotype detected in the anogenital area. There was a significant independent association between genital and anal HPV infections. Conclusion Anogenital HPV infection is common among Malaysian men. These findings emphasize the ubiquity of HPV infection and thus the value of population-wide access to HPV prevention. |
Databáze: | OpenAIRE |
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