Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population

Autor: Patti E. Gravitt, Yin Ling Woo, Nirmala Bhoo-Pathy, Pik Pin Goh, Su Pei Khoo, Shridevi Subramaniam, Zhang Lin, Jerome L. Belinson, Xinfeng Qu, Mohd Khairul Anwar Shafii, Siew Hwei Yap, Nazrila Hairizan Nasir
Rok vydání: 2021
Předmět:
Male
Viral Diseases
Epidemiology
Anal Canal
Pathology and Laboratory Medicine
Human Papillomavirus DNA Tests
Men who have sex with men
Geographical Locations
Medical Conditions
Genotype
Ethnicity
Prevalence
Medicine and Health Sciences
Multidisciplinary
Human papillomavirus 11
Cancer Risk Factors
HPV infection
virus diseases
Middle Aged
Anal canal
female genital diseases and pregnancy complications
Infectious Diseases
medicine.anatomical_structure
Oncology
Medical Microbiology
Viral Pathogens
Viruses
Medicine
Independent Living
Pathogens
Research Article
Adult
Human Papillomavirus Infection
medicine.medical_specialty
Asia
Adolescent
Papillomaviruses
Urology
Science
Sexually Transmitted Diseases
Men WHO Have Sex with Men
Genitalia
Male
HPV-18
Microbiology
medicine
Humans
Sex organ
Microbial Pathogens
Genotyping
Biology and life sciences
Genitourinary Infections
business.industry
Public health
Papillomavirus Infections
Malaysia
Organisms
Human Papillomavirus
Human papillomavirus 6
medicine.disease
Carriage
Socioeconomic Factors
Medical Risk Factors
People and Places
Population Groupings
DNA viruses
business
Sexuality Groupings
Demography
Zdroj: PLoS ONE, Vol 16, Iss 1, p e0245731 (2021)
PLoS ONE
ISSN: 1932-6203
Popis: Background Addressing the burden of HPV-associated diseases among men is increasingly becoming a public health issue. The main objective of this study was to determine HPV prevalence among a healthy community-based Malaysian men. Method This was a cross-sectional study that recruited 503 healthy males from 3 community-based clinics in Selangor, Malaysia. Genital and anal samples were collected from each participant for 14 high risk and 2 low risk HPV DNA detection and genotyping. All participants responded to a set of detailed sociodemographic and sexual behaviour questionnaire. Results The median age at enrolment was 40 years old (IQR: 31–50). The anogenital HPV6/11 prevalence was 3.2% whereas high risk HPV prevalence was 27.1%. The genital HPV prevalence for HPV6/11 was 2.9% while high risk HPV was 18.8%. HPV6/11 prevalence in the anal canal was 1.6% and high risk HPV was 12.7%. HPV 18 was the most prevalent genotype detected in the anogenital area. There was a significant independent association between genital and anal HPV infections. Conclusion Anogenital HPV infection is common among Malaysian men. These findings emphasize the ubiquity of HPV infection and thus the value of population-wide access to HPV prevention.
Databáze: OpenAIRE
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