The Relationship between Annual Airborne Pollen Levels and Occurrence of All Cancers, and Lung, Stomach, Colorectal, Pancreatic and Breast Cancers: A Retrospective Study from the National Registry Database of Cancer Incidence in Japan, 1975–2015
| Autor: | Yoshiyuki Kuroiwa, Akira Awaya |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Oncology
pollen diseases medicine.medical_specialty cancer incidence Health Toxicology and Mutagenesis pancreatic cancer lcsh:Medicine Context (language use) Breast Neoplasms specific intractable diseases medicine.disease_cause Article 03 medical and health sciences 0302 clinical medicine Breast cancer breast cancer Japan Internal medicine Pancreatic cancer Pollen Air Pollution Neoplasms otorhinolaryngologic diseases Medicine Humans Registries Lung cancer 030304 developmental biology Retrospective Studies 0303 health sciences Air Pollutants Cancer prevention Kawasaki disease business.industry Incidence Stomach lcsh:R Public Health Environmental and Occupational Health Cancer food and beverages Retrospective cohort study Environmental Exposure medicine.disease airborne pollen exposure lung cancer 030220 oncology & carcinogenesis business Colorectal Neoplasms |
| Zdroj: | International Journal of Environmental Research and Public Health, Vol 17, Iss 3950, p 3950 (2020) International Journal of Environmental Research and Public Health Volume 17 Issue 11 |
| ISSN: | 1661-7827 1660-4601 |
| Popis: | Suppression of risk factors including smoking, overdrinking and infections by human papilloma and hepatitis B and C viruses has been recommended for cancer prevention however, identification of other environmental risk factors has not been enough. Besides the 2003 report that Kawasaki disease may be triggered by pollen exposure, 40 Japanese specific intractable diseases have recently been reported as &ldquo pollen diseases,&rdquo also potentially triggered by pollen exposure．Various human organs are affected by pollen exposure, leading to systemic vasculitis autoimmune connective tissue diseases, inflammatory bowel diseases and intractable neuromuscular and bone diseases, suggesting the common effects of pollen exposure on fundamental functions of vital metabolism. In this context, cancer and malignant tumors may be another group of intractable diseases triggered by epigenetic pollen exposure. Thus, this study compared the number of newly registered patients with 24 types of cancer and airborne pollen levels measured from 1975 to 2015. We searched for statistical correlations with Bonferroni correction between the annual number of newly registered patients for all cancers or for each of lung, stomach, colorectal, pancreatic and breast cancers in the patient-registry year &ldquo x&rdquo and annual airborne pollen levels measured in the same year as &ldquo or 1&ndash 7 years prior to the year &ldquo The number of newly registered patients for lung, and pancreatic cancers in the patient-registry year &ldquo was highly correlated with airborne pollen levels measured 2 years prior to &ldquo That for breast cancer was correlated with pollen levels measured 2 and 5 years prior to &ldquo To our knowledge, this is the first rapid communication of the association between pollen levels and cancer incidence. |
| Databáze: | OpenAIRE |
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