Diagnosis of disorders in amino acid methabolism by chemical ionization mass spectrometry
| Autor: | David. Issachar, Jehuda Yinon |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Clinical Biochemistry
Urine Biochemistry Mass Spectrometry chemistry.chemical_compound Maple Syrup Urine Disease Phenylketonurias medicine Humans Amino acid metabolism Amino Acids Child chemistry.chemical_classification Chemical ionization Chromatography Cystinuria Ion exchange Chemistry Biochemistry (medical) General Medicine medicine.disease Amino acid Reagent Child Preschool Isobutane |
| Zdroj: | Clinica chimica acta; international journal of clinical chemistry. 73(2) |
| ISSN: | 0009-8981 |
| Popis: | A semi-quantitative method has been developed for rapid determination of amino acids and other nitrogenous compounds in human urine. The method uses direct chemical ionization mass spectrometry with isobutane as reagent. The nitrogenous compounds are separated from the urine samples by ion exchange. Disorders in amino acid metabolism have been determined by this method in patients suffering from phenylketonuria, cystinuria and maple-syrup urine disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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