Primary Lymphosarcoma of the Larynx in a Child
| Autor: | Byrne Wj, Feig S, Landing Bh, Isaacs H, Cohen |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Vincristine
medicine.medical_specialty Cyclophosphamide 03 medical and health sciences 0302 clinical medicine Maintenance therapy Bronchoscopy Prednisone Biopsy medicine Humans 030223 otorhinolaryngology Laryngeal Neoplasms Laryngoscopy medicine.diagnostic_test business.industry Lymphoma Non-Hodgkin General Medicine Airway obstruction medicine.disease Surgery Otorhinolaryngology Child Preschool 030220 oncology & carcinogenesis Female Methotrexate business medicine.drug |
| Zdroj: | Annals of Otology, Rhinology & Laryngology. 87:20-24 |
| ISSN: | 1943-572X 0003-4894 |
| DOI: | 10.1177/00034894780870s505 |
| Popis: | A 4 7/12-year-old Caucasian female with a history of “croup-like symptoms” and persistent airway obstruction, was found to have a primary lymphosarcoma by biopsy at the time of laryngoscopy and bronchoscopy. No metastatic disease was found. After an induction course of vincristine, prednisone and local irradiation, she received CNS prophylaxis with intrathecal methotrexate and cranial irradiation. Maintenance therapy, administered over a 2¾ year period, consisted of cyclophosphamide, methotrexate, and 6-mercaptopurine. Excluding the diagnostic evaluation, she was hospitalized only once for the management of suspected sepsis, gastrointestinal ulceration and severe bone marrow depression. Since discontinuing treatment 27 months ago, she has remained free of disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|