Depressive symptoms, physical symptoms, and health-related quality of life among older adults with HIV

Autor:	Jaimie P. Meyer, Wilson Vincent, Trace Kershaw, Timothy G. Heckman, Blair Olson, Nathan B. Hansen, Kathleen J. Sikkema
Rok vydání:	2019
Předmět:	Male Gerontology Aging medicine.medical_specialty Health Status Population Human immunodeficiency virus (HIV) HIV Infections Human physical appearance medicine.disease_cause Article 03 medical and health sciences 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) Quality of life Humans Medicine education Depressive symptoms Depression (differential diagnoses) Aged Depressive Disorder education.field_of_study Depression business.industry 030503 health policy & services Public health Public Health Environmental and Occupational Health Middle Aged medicine.disease United States Anti-Retroviral Agents 030220 oncology & carcinogenesis Quality of Life Female New York City 0305 other medical science business
Zdroj:	Qual Life Res
ISSN:	1573-2649 0962-9343
DOI:	10.1007/s11136-019-02271-0
Popis:	In the United States, approximately 45% of persons living with HIV (PLHIV) are ≥ 50 years of age. Many older PLHIV have multi-morbidities that complicate HIV infection and/or interfere with, or are exacerbated by, antiretroviral treatment. Physical health symptoms and psychiatric disorders, particularly depression, can worsen life quality in older PLHIV. This study assessed associations among physical symptoms, indicators of HIV-related health status (i.e., time since diagnosis; ever diagnosed with AIDS; having attained viral suppression), depressive symptoms, and health-related quality of life (HRQoL) in older PLHIV. Regression analyses examined data from 296 PLHIV ≥ 50 years of age living in Cincinnati, OH, Columbus, OH, and New York City. Depressive symptoms and physical symptoms, particularly those related to appearance and sexual functioning, most strongly predicted HRQoL. Indicators of HIV health status did not significantly predict HRQoL. Depressive symptoms were a particularly robust predictor of HRQoL, even when accounting for physical health symptoms. Findings suggest that symptom management is critical to HRQoL in older PLHIV, and symptoms related to physical appearance and sexual functioning should not be overlooked in this growing population.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5cf5682c60b81069e5ca46fc6ed2300 https://doi.org/10.1007/s11136-019-02271-0 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.