Acute effect of cola and caffeine on locomotor activity in drosophila and rat
| Autor: | Peter Celec, M Marônek, K Kmeťová, Július Hodosy, Veronika Borbélyová |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Time Factors Physiology Short Communication Carbonated Beverages Acute effect Locomotor activity Cola (plant) Open field 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Caffeine Internal medicine medicine Animals Drosophila biology General Medicine biology.organism_classification Drosophila melanogaster 030104 developmental biology Endocrinology chemistry Central Nervous System Stimulants Open Field Test Locomotion 030217 neurology & neurosurgery |
| Zdroj: | Physiol Res |
| ISSN: | 1802-9973 0862-8408 |
| Popis: | Caffeine is well known for reducing fatigue and its effect on behavior is widely studied. Usually, caffeine is not ingested in its pure form but rather in sugar-sweetened beverages such as cola. Our aim was to compare the acute effect of cola and caffeine on locomotor activity. Rats and flies ingested cola or caffeine solution for 24 hours. The open field test revealed higher locomotor activity in cola groups for both flies and rats. Surprisingly, no differences have been observed between caffeine and control group. We conclude that caffeine itself does not explain the effect of cola on locomotor activity. Effect of cola cannot be generalized and interpreted for any caffeinated drink with other contents. Rather, the observed effect on locomotor activity may be caused by interaction of caffeine with other substances present in cola. |
| Databáze: | OpenAIRE |
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