Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice
Autor: | Meejung Ahn, Bong-Jo Kang, Yeoung-Hwan Jang, Hyojin Bang |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Genotype Food-borne disease Veterinary (miscellaneous) Parasitic Diseases Animal 030231 tropical medicine Flounder ST3 genotype Host Specificity Microbiology lcsh:Infectious and parasitic diseases 03 medical and health sciences Feces Fish Diseases Mice Kudoa septempunctata 0302 clinical medicine Food Parasitology Species Specificity Republic of Korea Bioassay Animals lcsh:RC109-216 Intestinal Diseases Parasitic Myxozoa Gastrointestinal tract biology Virulence fungi 030108 mycology & parasitology biology.organism_classification Spore Animals Suckling Specific Pathogen-Free Organisms Infectious Diseases Insect Science Kudoa Cytokines Animal Science and Zoology Parasitology Biological Assay suckling mice Research Article Paralichthys olivaceus |
Zdroj: | Parasite, Vol 23, p 18 (2016) Parasite |
ISSN: | 1776-1042 |
Popis: | This study investigated the effects of Kudoa septempunctata genotype ST3 spores on ddY suckling mice. Purified Kudoa septempunctata spores were administered into the stomachs of the mice at 5 × 10(6) or 5 × 10(7) spores/mouse, with inactivated Kudoa (5 × 10(6) spores/mouse) or vehicle as controls. No abnormal clinical symptoms were observed and there were no variations in fluid accumulation ratio and cytokine gene expression in all groups. In addition, intact Kudoa spores and the 18S rDNA gene were only detected (by microscopy and quantitative PCR, respectively) in the groups administered such spores. This study thus confirms that spores from the ST3 strain of Kudoa septempunctata were excreted in the faeces without infecting the gastrointestinal tract in ddY suckling mice. |
Databáze: | OpenAIRE |
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