Internal anal sphincter activity after restorative proctocolectomy for ulcerative colitis

Autor: P. M. Sagar, M. E. R. Williamson, P. J. Holdsworth, Wyn G. Lewis, David B. R. Johnston
Rok vydání: 1994
Předmět:
Zdroj: Diseases of the Colon & Rectum. 37:32-36
ISSN: 0012-3706
Popis: PURPOSE: The aim of this study was to further investigate continuous ambulatory anal manometry which has recently been introduced as a method for studying anorectal activity in ambulant patients, thereby avoiding many of the potential drawbacks of static techniques. METHOD: In this study continuous ambulatory manometry was used to assess the activity of the internal anal sphincter in patients who had undergone restorative proctocolectomy, and, in particular, to compare patients who had undergone conventional mucosal proctectomy with sutured endoanal, ileoanal anastomosis with patients who had undergone restorative proctocolectomy with preservation of the entire anal canal by means of stapled, end-to-end, ileoanal anastomosis without mucosectomy. RESULTS: Evidence of basal internal sphincter activity was found in only 38 percent of patients after mucosal proctectomy with sutured endoanal anastomosis, whereas all patients after restorative proctocolectomy with stapled end-to-end anastomosis and all control individuals showed such activity of the internal sphincter. Similarly, the number of sampling episodes seen in patients after mucosal proctectomy with endoanal anastomosis was significantly less (median, 0.0/hours (0–30/hours)) than the number of sampling episodes observed in patients after end-to-end anastomosis (median, 4.5/hours (1–48/hours)) or in control individuals (median, 5.6/hours (0–31/hours)) (P
Databáze: OpenAIRE
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