Television viewing and fatty liver in early midlife. The Cardiovascular Risk in Young Finns Study
| Autor: | Vera Mikkilä, Katja Pahkala, Jorma Viikari, Nina Hutri-Kähönen, Tuija Tammelin, Terho Lehtimäki, Harri Helajärvi, Olli J. Heinonen, Olli T. Raitakari, Markus Juonala, Mervi Oikonen, Mika Kähönen |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Television viewing Waist Population Gastroenterology Body Mass Index 03 medical and health sciences 0302 clinical medicine Non-alcoholic Fatty Liver Disease Risk Factors Internal medicine medicine Humans 030212 general & internal medicine Longitudinal Studies Gamma-glutamyltransferase education Finland Triglycerides Sedentary lifestyle Ultrasonography education.field_of_study biology business.industry Fatty liver Body Weight General Medicine gamma-Glutamyltransferase Middle Aged medicine.disease Obesity 3. Good health Endocrinology Cardiovascular Diseases biology.protein 030211 gastroenterology & hepatology Female Television Sedentary Behavior Waist Circumference business Body mass index |
| Zdroj: | Annals of medicine. 47(6) |
| ISSN: | 1365-2060 |
| Popis: | Both sedentary behaviour and fatty liver are associated with increased risk of obesity and non-communicable diseases, but their relationship remains unknown. We investigated the relationship of television (TV) viewing time with serum gamma-glutamyltransferase (GGT) and Fatty Liver Index (FLI), and ultrasonographically assessed liver fat.A total of 1,367 adults of the population-based Cardiovascular Risk in Young Finns study (748 women, 619 men, aged 34-49 years) had fasting serum GGT, triglycerides, weight, height, and waist circumference, and self-reported TV time data from 2001, 2007, and 2011. Changes in GGT and FLI, and liver ultrasound images in 2011 were studied in groups with constantly low (≤ 1 h/d), moderate (1-3 h/d), or high (≥ 3 h/d) daily TV time, and in groups with ≥ 1 hour increase/decrease in daily TV time between 2001 and 2011.Constantly high TV time was associated with higher GGT and FLI (P0.02 in both), and 2.3-fold (95% CI 1.2-4.5) increased risk of fatty liver regardless of age, sex, leisure-time and occupational physical activity, energy intake, diet composition, alcohol use, sleep duration, socioeconomic status, and smoking. Adjustment for BMI partly attenuated the associations.High TV viewing increases fatty liver risk. It may be one mechanism linking sedentary behaviour with increased cardiometabolic disease risks. |
| Databáze: | OpenAIRE |
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