| Autor: |
Mahabul Haque, Sona Lyndem, Atanu Singha Roy |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Luminescence : the journal of biological and chemical luminescenceREFERENCES. 37(5) |
| ISSN: |
1522-7243 |
| Popis: |
The synthesis of small-sized quantum dots (QDs) (1-10 nm) via the green route has garnered great interest regarding their prospective use in many biological applications (diagnosis, drug delivery and in vivo sensing); this is difficult to achieve using chemical synthesis methods, which produce larger size QD particles and also require hazardous reagents. Here, we synthesized biogenic cadmium sulphide (CdS) QDs using green tea extract as the reducing agent to produce particles that were homogeneous and a smaller size of 2-4 nm. We also elucidated the (a) protein binding, (b) antibacterial use and (c) sensing applications of biogenic CdS QDs in this present work. The biosynthesized CdS QDs were found to have extensive antibacterial activity against both Gram-negative Escherichia coli and Gram-positive Enterococcus faecalis bacterial strains. The introduction of QDs in biological medium can lead to the formation of protein-QD complexes; therefore we investigated the binding interaction of CdS QDs with the carrier protein human serum albumin (HSA) in vitro. The synthesized CdS QDs quenched the intrinsic fluorescence of HSA through a static quenching mechanism and the binding constant (K |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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