A Unified Strategy for the Asymmetric Synthesis of Highly Substituted 1,2-Amino Alcohols Leading to Highly Substituted Bisoxazoline Ligands

Autor:	Scott E. Denmark, Casey L. Olen, Yang Wang, Bijay Shrestha, Adon C. Kwong, Aaron Roth, Brennan T. Rose
Rok vydání:	2021
Předmět:	010405 organic chemistry Chemistry Organic Chemistry Enantioselective synthesis Stereoisomerism Ligands 010402 general chemistry Amino Alcohols 01 natural sciences Combinatorial chemistry 0104 chemical sciences Yield (chemistry) Indicators and Reagents Imines
Zdroj:	The Journal of Organic Chemistry. 86:3490-3534
ISSN:	1520-6904 0022-3263
DOI:	10.1021/acs.joc.0c02899
Popis:	A general procedure for the asymmetric synthesis of highly substituted 1,2-amino alcohols in high yield and diastereoselectivity is described that uses organometallic additions of a wide range of nucleophiles to
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ac603ddcf819ade3001b1eb57337f8 https://doi.org/10.1021/acs.joc.0c02899 Zobrazit plný text záznamu