Treatment of experimental cutaneous leishmaniasis with liposome-intercalated amphotericin B
| Autor: | C B Panosian, Michael Barza, D J Wyler, Francis C. Szoka |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Leishmania tropica
Ratón medicine.medical_treatment Pharmacology Mice Cutaneous leishmaniasis Amphotericin B parasitic diseases Medicine Animals Pharmacology (medical) Leishmaniasis Leishmania Liposome Chemotherapy Mice Inbred BALB C biology business.industry medicine.disease biology.organism_classification Mice Inbred C57BL Infectious Diseases Immunology Liposomes Female business medicine.drug Research Article |
| Zdroj: | Antimicrobial agents and chemotherapy. 25(5) |
| ISSN: | 0066-4804 |
| Popis: | The therapeutic efficacy of a liposomal preparation of amphotericin B was evaluated in two murine models of cutaneous leishmaniasis. No significant decrease in tissue parasite density was observed in C57BL/6 mice after systemic treatment instituted seven days after footpad inoculation with Leishmania tropica; in contrast, BALB/c mice showed a modest response. |
| Databáze: | OpenAIRE |
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