Impact of symptom severity in patients with diarrhoea-predominant irritable bowel syndrome (IBS-D): results from two separate surveys of HCPs and patients with IBS-D

Autor: Stephen Baker, Anton Emmanuel, Gwen Wiseman, Richard Goosey, Hans Törnblom
Rok vydání: 2020
Předmět:
Adult
Diarrhea
Male
Canada
Health Knowledge
Attitudes
Practice

Gastrointestinal symptom rating scale
medicine.medical_specialty
Abdominal pain
Attitude of Health Personnel
Patient characteristics
macromolecular substances
Severity of Illness Index
Irritable Bowel Syndrome
Cost of Illness
Quality of life
IBS
Internal medicine
medicine
Humans
In patient
Patient Reported Outcome Measures
Diarrhoea-predominant irritable bowel syndrome
lcsh:RC799-869
Irritable bowel syndrome
Retrospective Studies
Internet
Patient-reported outcomes
business.industry
Australia
Gastroenterology
Symptom severity
General Medicine
Middle Aged
Hepatology
medicine.disease
Health Surveys
Europe
Outcomes research
Health Care Surveys
lcsh:Diseases of the digestive system. Gastroenterology
Female
medicine.symptom
business
Research Article
Zdroj: BMC Gastroenterology
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-10 (2020)
ISSN: 1471-230X
DOI: 10.1186/s12876-020-01252-9
Popis: Background Management of diarrhoea-predominant irritable bowel syndrome (IBS-D) is generally based on patient-reported symptoms; however, limited information on symptom severity exists. The objective of the study was to assess the impact of IBS-D severity on patient burden and patient and healthcare professional attitudes towards IBS. Methods We conducted two web-based surveys of healthcare professionals and patients from Australia, Canada and Europe. We analysed patient characteristics and attitudes by IBS-D severity, which was assessed retrospectively using a composite of four variables: worst abdominal pain, IBS symptom frequency, Bristol Stool Form Scale and quality of life. Results Of 679 healthcare professional respondents, one-third routinely classified patients by severity. The patient survey was completed by 513 patients with mild (26%), moderate (33%) and severe (41%) IBS-D, classified using the composite scale. Age, sex and treatment satisfaction did not change with severity; however, 19% of patients classified with severe IBS-D agreed with the statement: ‘When my IBS is bad, I wish I was dead’ versus 4 and 7% of patients with mild and moderate IBS-D, respectively (p Conclusion Compared with milder symptoms, severe IBS-D was associated with increased medication use and a negative perspective of IBS-D. This highlights the need for a validated severity scale to inform treatment decisions.
Databáze: OpenAIRE