Behavior of the renal kallikrein in spontaneously hypertensive rats: Influence of sexual hormones and aldosterone-sensitive distal nephron ion channels

Autor: Pablo Javier, Azurmendi, Ayelén Rayen, Toro, Alejandro Fabián, Celía, Darío, Guevara, Martín Rogelio, Solerno, Luis Alberto, Di Ciano, Jorge Eduardo, Toledo, Fernando Raúl, Ibarra, Elvira Emilia, Arrizurieta, Elisabet Mónica, Oddo
Rok vydání: 2023
Předmět:
Zdroj: Peptides. 160:170925
ISSN: 0196-9781
Popis: The renal kallikrein-kinin system (RKKS) has been related to blood pressure control and sodium and water balance. We have previously shown that female spontaneously hypertensive rats (SHR) have high urinary kallikrein activity (UKa) and lower blood pressure (BP) than males whereas ovariectomy stimulates UKa and diminishes BP. We also showed that high K
Databáze: OpenAIRE