Painful limbs/moving extremities
| Autor: | Andreas A. Argyriou, Spiridon Papapetropoulos |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Central Nervous System
medicine.medical_specialty Movement disorders Central nervous system Fingers Central nervous system disease Physical medicine and rehabilitation medicine Humans Peripheral Nerves Muscle Skeletal Movement Disorders business.industry Extremities General Medicine Toes medicine.disease Botulinum toxin Pathophysiology Pain Intractable Surgery Peripheral Functional imaging Electrophysiology medicine.anatomical_structure Neurology Neurology (clinical) medicine.symptom business medicine.drug |
| Zdroj: | Acta Neurologica Scandinavica. 117:224-230 |
| ISSN: | 1600-0404 0001-6314 |
| Popis: | Painful limbs/moving extremities (PLME) is a disorder characterized by spontaneous, complex, slow (1-2 Hz) involuntary toe or finger movements. The movements that can be bilateral or unilateral are usually accompanied by pain in the affected limbs. Painless variants are less common. PLME has been associated with peripheral and central nervous system disease although idiopathic cases have been reported. Its etiopathogenesis is unknown and treatment approaches remain largely empirical. Nerve blocks and botulinum toxin type A injections as well as oral medication have had some measure of success. Current theories suggest that central oscillator(s) at the spinal or supraspinal levels may be involved. Future research in PLME should include prospective electrophysiological and functional imaging studies as well as clinical trials with botulinum toxin injections and oral pharmacological agents. |
| Databáze: | OpenAIRE |
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