Photocatalytic Isocyanide-Based Multicomponent Domino Cascade toward the Stereoselective Formation of Iminofurans

Autor:	Antonella Ilenia Alfano, Davide Ravelli, Gian Cesare Tron, Sveva Pelliccia, Mariateresa Giustiniano, Ettore Novellino, Alberto Massarotti, Paolo Luciano
Přispěvatelé:	Pelliccia, S., Alfano, A. I., Luciano, P., Novellino, E., Massarotti, A., Tron, G. C., Ravelli, D., Giustiniano, M.
Rok vydání:	2019
Předmět:	010405 organic chemistry Chemistry Isocyanide Organic Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry Domino 0104 chemical sciences chemistry.chemical_compound Cascade Photocatalysis Reactivity (chemistry) Domino process Stereoselectivity
Zdroj:	The Journal of Organic Chemistry. 85:1981-1990
ISSN:	1520-6904 0022-3263
DOI:	10.1021/acs.joc.9b02709
Popis:	A visible-light-promoted three-component isocyanide-based synthesis of iminofurans is herein reported. The reaction proved to be general in scope and proceeds through a triple domino process. Control experiments with 18O-labeled water and TEMPO provided key mechanistic insights for delineating the reactivity paradigms crucial to design efficient photoredox isocyanide-based domino transformations.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a580759bbdfca51d19dbad39f8c5b419 https://doi.org/10.1021/acs.joc.9b02709 Zobrazit plný text záznamu