Effectiveness of allergy testing in milk induced eosinophilic esophagitis. Description and follow-up of patients
| Autor: | B De la Hoz, S Terrados, Cristina Camarero, Laura Sánchez-Ruano, Liseth Villafana, Javier Martínez-Botas, Darío Antolín-Amérigo |
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| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Adolescent Immunology Allergy testing Milk allergy Immunoglobulin E Culprit Internal medicine Eosinophilic medicine Immunology and Allergy Animals Humans Eosinophilic esophagitis Child Retrospective Studies Skin Tests biology Esophageal disease business.industry food and beverages General Medicine Eosinophilic Esophagitis Allergens medicine.disease Prognosis Milk Treatment Outcome Child Preschool biology.protein Female Milk Hypersensitivity business Esophagitis Follow-Up Studies |
| Zdroj: | Allergologia et immunopathologia. 48(6) |
| ISSN: | 1578-1267 |
| Popis: | Introduction Eosinophilic esophagitis (EoE) is a chronic, local immune-mediated esophageal disease that has been on the increase lately. There is currently enough evidence to conclude that EoE is an allergic disorder triggered by food allergens, with cow’s milk (CM) being the most frequent. Dietary intervention is the first-line approach. This study aimed to assess the clinical characteristics, the diagnostic method, and the prognosis of patients whose culprit food was CM, as opposed to other triggers. Methods Children with EoE evaluated in our pediatric Allergy Department were retrospectively studied from 2004 to 2017. We collected clinical variables, diagnostic protocol, treatment, and follow-up data. We compared patients whose culprit food was CM and patients with EoE due to other causative agents. Results We analyzed 31 children with EoE and found the causative food to be cow’s milk in 14 (45%). Clinical characteristics were similar in patients with EoE due to milk or any other cause. Eight of 14 patients with milk-induced EoE (57.14%) presented positive skin prick test results against cow’s milk. All patients had positive IgE against cow’s milk. None of the patients had any other food as the trigger. The median follow-up was 2.68 years (6 months to 9 years) with initial remission of 100%. Conclusion Testing-based elimination diets effectively treated all of the patients with milk-induced EoE. The advantage of this diagnostic protocol is that it required a mean of only two foods to be tested, significantly smaller number than in empiric diets. |
| Databáze: | OpenAIRE |
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