Epidemiological investigation of the first 5685 cases of SARS-CoV-2 infection in Qatar, 28 February–18 April 2020
| Autor: | Einas Al Kuwari, Roberto Bertollini, Peter Coyle, Laith J. Abu-Raddad, Hamad Eid Al Romaihi, Ali Nizar Latif, Zaina Al Kanaani, Hanan F. Abdul Rahim, Robert Owen, Adeel A. Butt, Hanan M. Al Kuwari, Salih Al Marri, Mohamed H. Al Thani, Abdul-Badi Abou-Samra, Muna Al Masalmani, Abdullatif Al Khal |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Adolescent Pneumonia Viral Population Comorbidity Severe Acute Respiratory Syndrome Severity of Illness Index Asymptomatic Disease Outbreaks Betacoronavirus Young Adult Epidemiology Severity of illness Diabetes Mellitus medicine Humans Young adult education Asymptomatic Infections Pandemics Qatar education.field_of_study SARS-CoV-2 Transmission (medicine) business.industry Public health public health COVID-19 General Medicine Middle Aged medicine.disease Hypertension Medicine Female epidemiology Public Health medicine.symptom Coronavirus Infections business |
| Zdroj: | BMJ Open BMJ Open, Vol 10, Iss 10 (2020) |
| ISSN: | 2044-6055 |
| Popis: | ObjectiveTo define the epidemiological curve of COVID-19 in Qatar and determine factors associated with severe or critical illness.DesignCase series of first 5685 COVID-19 cases in Qatar.Setting and participantsAll confirmed COVID-19 cases in the State of Qatar between 28 February and 18 April 2020.Main outcome measuresNumber of total and daily new COVID-19 infections; demographic characteristics and comorbidity burden and severity of infection; factors associated with severe or critical illness.ResultsBetween 28 February and 18 April 2020, 5685 cases of COVID-19 were identified. Median age was 34 (IQR 28–43) years, 88.9% were male and 8.7% were Qatari nationals. Overall, 83.6% had no concomitant comorbidity, and 3.0% had three or more comorbidities. The overwhelming majority (90.9%) were asymptomatic or with minimal symptoms, with 2.0% having severe or critical illness. Seven deaths were observed during the time interval studied. Presence of hypertension or diabetes was associated with a higher risk of severe or critical illness, but age was not. The epidemiological curve indicated two distinct patterns of infection, a larger cluster among expatriate craft and manual workers and a smaller one among Qatari nationals returning from abroad during the epidemic.ConclusionCOVID-19 infections in Qatar started in two distinct clusters, but then became more widespread in the population through community transmission. Infections were mostly asymptomatic or with minimal symptoms and associated with very low mortality. Severe/critical illness was associated with presence of hypertension or diabetes but not with increasing age. |
| Databáze: | OpenAIRE |
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