Muscle Insulin Resistance in Youth with Obesity and Normoglycemia Is Associated with Altered Fat Metabolism

Autor:	Ann Scherzinger, Kristen J. Nadeau, Amy Baumgartner, Laura Pyle, Melanie Cree-Green, Bryan C. Bergman, Samantha Bacon, Pattara Wiromrat, Jessica Thurston, Jacob J. Stuppy
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Adult Male medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism medicine.medical_treatment Medicine (miscellaneous) Adipose tissue 030209 endocrinology & metabolism Article 03 medical and health sciences Young Adult 0302 clinical medicine Endocrinology Insulin resistance Internal medicine medicine Prevalence Lipolysis Humans 030212 general & internal medicine Obesity Exercise physiology Child Muscle Skeletal Exercise chemistry.chemical_classification Nutrition and Dietetics business.industry Insulin Fatty acid Lipid metabolism medicine.disease Lipid Metabolism chemistry Female Insulin Resistance business
Zdroj:	Obesity (Silver Spring)
Popis:	OBJECTIVE This study aimed to phenotype and compare adipose, hepatic, and muscle insulin sensitivity (IS) in a diet- and physical activity-controlled cohort of normoglycemic youth with obesity with that of participants without obesity (controls) to distinguish early metabolic abnormalities in pediatric obesity. METHODS Thirty-eight participants (17 in the control group [BMI
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57076f0173912de7d57691a05a8cdf4 https://europepmc.org/articles/PMC6897373/ Zobrazit plný text záznamu