International Society of Urological Pathology (ISUP)-Grade Grouping in Prostatic Adenocarcinoma and its Prognostic Implications
Autor: | Atif Ali Hashmi, Syeda Narisa Iftikhar, Shahzeb Munawar, Omer Ahmed, Syed Rafay Yaqeen, Ishaq Azeem Asghar, Muhammad Irfan, Javaria Ali, Muhammad M. Edhi, Shumaila Kanwal Hashmi |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Cancer Investigation. 40:211-218 |
ISSN: | 1532-4192 0735-7907 |
Popis: | In this study, we evaluated the association of ISUP/WHO-grade groups with various pathological prognostic parameters and cancer-specific survival in patients with prostatic adenocarcinoma. We found 27 (15.7%) cases of grade group 1, 22 (12.8%) grade group 2, 30 (17.4%) grade group 3, 40 (23.3%) grade group 4 and 53 (30.8%) grade group 5 prostatic adenocarcinoma. We found that high-grade tumors (grade 3-5) had a higher frequency of perineural invasion and higher tumor volumes (50%). Moreover, a significant association of tumor grade was noted with cancer-specific survival of patients, signifying prognostic significance of grade grouping in prostatic adenocarcinoma. |
Databáze: | OpenAIRE |
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