Optical Sensor for Real-Time pH Monitoring in Human Tissue
| Autor: | Vitaly Efremov, Alicja Kaworek, Colette McDonagh, Roger C. N. McMorrow, Tobias Abel, Garret Coady, Dorota Wencel, Aidan Bradford, Denise Carthy |
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| Rok vydání: | 2018 |
| Předmět: |
Optical fiber
Materials science 02 engineering and technology 010402 general chemistry 01 natural sciences Ph monitoring law.invention Biomaterials law In vivo Fiber Optic Technology Humans General Materials Science A fibers Plastic optical fiber Optical Fibers Reproducibility Response time General Chemistry Hydrogen-Ion Concentration 021001 nanoscience & nanotechnology 0104 chemical sciences Ph sensing 0210 nano-technology Biotechnology Biomedical engineering |
| Zdroj: | Small (Weinheim an der Bergstrasse, Germany). 14(51) |
| ISSN: | 1613-6829 |
| Popis: | This article reports on a fiber-based ratiometric optical pH sensor for use in real-time and continuous in vivo pH monitoring in human tissue. Stable hybrid sol-gel-based pH sensing material is deposited on a highly flexible plastic optical fiber tip and integrated with excitation and detection electronics. The sensor is extensively tested in a laboratory environment before it is applied in vivo in a human model. The pH sensor performance in the laboratory environment outperforms the state-of-the-art reported in the current literature. It exhibits the highest sensitivity in the physiological pH range, resolution of 0.0013 pH units, excellent sensor to sensor reproducibility, long-term stability, short response time of |
| Databáze: | OpenAIRE |
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