Radium-induced malignant tumors of the mastoid and paranasal sinuses
| Autor: | Kirsh Ie, Keane At, Littman Ms |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Adult
Male medicine.medical_specialty Neoplasms Radiation-Induced Radiography Skull Neoplasms chemistry.chemical_element Autopsy Adenocarcinoma Bone Sarcoma Mastoid Radium Mucoepidermoid carcinoma Rhabdomyosarcoma medicine Carcinoma Humans Radiology Nuclear Medicine and imaging Radiometry Sinus (anatomy) Aged business.industry Environmental Exposure General Medicine Middle Aged medicine.disease Surgery Occupational Diseases medicine.anatomical_structure Paranasal sinuses chemistry Carcinoma Squamous Cell Body Burden Female business Paranasal Sinus Neoplasms |
| Zdroj: | American Journal of Roentgenology. 131:773-785 |
| ISSN: | 1546-3141 0361-803X |
| Popis: | In the records of 5,058 persons with therapeutic or occupational exposure to radium, 21 patients with carcinoma of the mastoid and 11 with malignant tumors of the paranasal sinuses were identified. Tumor induction times were 21-50 years for mastoid tumors (median, 33) and 19-52 years for paranasal sinus tumors (median, 34). Dosimetric data are given for the patients whose body burdens of radium have been measured. We found a high proportion of mucoepidermoid carcinoma, comprising 38% of the mastoid and 36% of the paranasal sinus tumors. Three patients had antecedent bone sarcoma at 20, 11, and 5 years, respectively, and a bone sarcoma was discovered at autopsy in a fourth patient. Radiographic changes in the mastoid and paranasal sinuses were similar to those seen in nonradium malignant tumors. More than 800 known persons exposed to radium before 1930 and another group of unknown size who received radium water or injections of radium from physicians are still alive and at risk of developing malignant tumors of the mastoid and paranasal sinuses. |
| Databáze: | OpenAIRE |
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