Economic impact of ovarian stimulation with corifollitropin alfa versus conventional daily gonadotropins in oocyte donors: a randomized study
| Autor: | Carlos Blanes, Manuel Sevilla Muñoz, Diana Collado, Antonio Requena, Enrique Solbes, María Cruz, Pilar Alamá |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Adult medicine.medical_specialty Menotropins Cost effectiveness Stimulation Reproductive technology law.invention 03 medical and health sciences Young Adult 0302 clinical medicine Randomized controlled trial Ovulation Induction law medicine Humans Economic impact analysis Gynecology 030219 obstetrics & reproductive medicine Oocyte Donation Obstetrics business.industry Obstetrics and Gynecology Oocyte Recombinant Proteins 030104 developmental biology medicine.anatomical_structure Reproductive Medicine Economic evaluation Female Follicle Stimulating Hormone Human business Developmental Biology |
| Zdroj: | Reproductive biomedicine online. 34(6) |
| ISSN: | 1472-6491 |
| Popis: | Assisted reproductive technologies are well-established treatments for many types of subfertility representing substantial economic and healthcare implications for patients, healthcare providers and society as a whole. In order to optimize outcomes according to the type of gonadotrophins within an oocyte donor programme, we performed an economic evaluation based on data collected in a multicentre, prospective, randomized study within three private clinics belonging to the IVI Group. Results showed no relevant between-group differences in the clinical variables. According to the economic analysis, ovarian stimulation with corifollitropin alfa increased the overall cost of the treatment as well as the cost per retrieved and effective oocyte, although the differences were not statistically significant. In conclusion, cost savings can be achieved using cheaper gonadotrophins during ovarian stimulation. The cost of corifollitropin alfa compared with recombinant FSH and highly purified human menopausal gonadotrophin should be considered when making treatment decisions. |
| Databáze: | OpenAIRE |
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