Road to remission: a comprehensive review of therapy in uveitis
| Autor: | Charles Stephen Foster, Ana M. Suelves, Sana S. Siddique, Rajiv Shah |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
genetic structures Disease Eye Uveitis Adrenal Cortex Hormones medicine Animals Humans Pharmacology (medical) Intensive care medicine Ocular inflammation Randomized Controlled Trials as Topic Pharmacology Clinical Trials as Topic Blindness business.industry Remission Induction General Medicine Immune modulation medicine.disease Surgery Expert opinion Clinical safety Corticosteroid use sense organs business Immunosuppressive Agents |
| Zdroj: | Expert Opinion on Investigational Drugs. 20:1497-1515 |
| ISSN: | 1744-7658 1354-3784 |
| DOI: | 10.1517/13543784.2011.617741 |
| Popis: | Although uveitis remains the third leading cause of preventable blindness in the US, the care and management of patients with uveitis and ocular inflammatory disease sit poised to make evolutionary if not revolutionary changes in the years ahead. This review serves to highlight important advances in the pharmacologic options available for the treatment of uveitis and ocular inflammation.Advances in steroid therapy (both topical and extended delivery), updates in the clinical safety of systemic immune modulation, and the emerging therapies for uveitis and ocular inflammatory disease are some of the areas covered in this review.Corticosteroids have been the mainstay in the care of patients with ocular inflammatory disorders for many years. Indeed, some physicians still use only steroids for treating inflamed eyes. However, the mission is remission of all corticosteroids in order to prevent the complications associated with long-term corticosteroid use. The goal is to achieve quiescence through aggressive use of corticosteroids to extinguish the fire and then move along to achieve steroid-free remission through immunosuppressant agents. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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