Rational case management of malaria with a rapid diagnostic test, Paracheck Pf®, in antenatal health care in Bangui, Central African Republic

Autor: Alexandre Manirakiza, Jean Delmont, Eugène Serdouma, Nestor Madji, Alain Le Faou, Luc Salva Heredeïbona, Georges Soula, Djibrine Djalle, Methode Moyen
Přispěvatelé: Institut Pasteur de Bangui, Réseau International des Instituts Pasteur (RIIP), Aix-Marseille Université - Faculté de médecine (AMU MED), Aix Marseille Université (AMU), Reproductive Health, Ministry of Public Health, Population and AIDS Control, Ministry of Public Health, RCA, Faculty of Health Sciences, University of Bangui, Université de Bangui, Ministry of Public Health, Population and AIDS Control, Castors Health Centre, Ministry of Public Health RCA, Malaria Programme Division, Ministry of Public Health, Population and AIDS Control, Ministry of Health [Mozambique], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Adult
medicine.medical_specialty
Pediatrics
Time Factors
030231 tropical medicine
Population
Prenatal care
Rapid diagnostic test
Drug Prescriptions
03 medical and health sciences
Antimalarials
Young Adult
0302 clinical medicine
Pregnancy
Health care
medicine
Humans
030212 general & internal medicine
Prospective Studies
education
Prospective cohort study
education.field_of_study
business.industry
Diagnostic Tests
Routine
lcsh:Public aspects of medicine
1. No poverty
Public Health
Environmental and Occupational Health
Prenatal Care
lcsh:RA1-1270
medicine.disease
3. Good health
Malaria
Central African Republic
Treatment Outcome
Case-Control Studies
Pregnancy Complications
Parasitic
Cohort
Emergency medicine
Female
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
business
Case Management
Cohort study
Research Article
Zdroj: BMC Public Health
BMC Public Health, BioMed Central, 2012, 12, pp.482. ⟨10.1186/1471-2458-12-482⟩
BMC Public Health, Vol 12, Iss 1, p 482 (2012)
ISSN: 1471-2458
Popis: Background Both treatment and prevention strategies are recommended by the World Health Organization for the control of malaria during pregnancy in tropical areas. The aim of this study was to assess use of a rapid diagnostic test for prompt management of malaria in pregnancy in Bangui, Central African Republic. Methods A cohort of 76 pregnant women was screened systematically for malaria with ParacheckPf® at each antenatal visit. The usefulness of the method was analysed by comparing the number of malaria episodes requiring treatment in the cohort with the number of prescriptions received by another group of pregnant women followed-up in routine antenatal care. Results In the cohort group, the proportion of positive ParacheckPf® episodes during antenatal clinics visits was 13.8%, while episodes of antimalarial prescriptions in the group which was followed-up routinely by antenatal personnel was estimated at 26.3%. Hence, the relative risk of the cohort for being prescribed an antimalarial drug was 0.53. Therefore, the attributable fraction of presumptive treatment avoided by systematic screening with ParacheckPf® was 47%. Conclusions Use of a rapid diagnostic test is useful, affordable and easy for adequate treatment of malaria in pregnant women. More powerful studies of the usefulness of introducing the test into antenatal care are needed in all heath centres in the country and in other tropical areas.
Databáze: OpenAIRE
Externí odkaz: