Lance–Adams syndrome associated with cerebellar pathology
| Autor: | Leema Reddy Peddareddygari, Ahmed Dirweesh, Fausto M. Ordonez, Raji P. Grewal, Charles Kososky, Adam Waddell |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
lcsh:Internal medicine Pathology medicine.medical_specialty cardiopulmonary arrest medicine.medical_treatment Case Report Case Reports Neurological disorder neurological complication 03 medical and health sciences 0302 clinical medicine Internal Medicine medicine cerebellar lesion Cardiopulmonary resuscitation lcsh:RC31-1245 Lance–Adams syndrome medicine.diagnostic_test business.industry Magnetic resonance imaging medicine.disease Pathophysiology 030104 developmental biology Etiology Successful resuscitation medicine.symptom business Myoclonus 030217 neurology & neurosurgery Emission computed tomography |
| Zdroj: | Journal of Community Hospital Internal Medicine Perspectives, Vol 7, Iss 3, Pp 182-184 (2017) Journal of Community Hospital Internal Medicine Perspectives |
| ISSN: | 2000-9666 |
| DOI: | 10.1080/20009666.2017.1340730 |
| Popis: | Lance–Adams syndrome (LAS) is an uncommon neurological disorder characterized by the development of chronic post-hypoxic myoclonus. There are relatively few cases described following successful cardiopulmonary resuscitation. We report a patient who developed LAS 3 months after successful resuscitation. Cerebral imaging studies indicate that brain pathology in LAS patients is not uniform, suggesting that the pathophysiology of myoclonus may vary from patient to patient. Our patient adds to this etiological heterogeneity by demonstrating the unusual feature of cerebellar pathology by both cerebral magnetic resonance imaging and single-photon emission computed tomography scans. There is also heterogeneity of these patients in their response to therapy. Unlike some patients described in the literature, our patient has not responded to drug treatment. Studies of these rare patients with LAS are important as they provide insight into the pathophysiology of this condition which, it is hopefully, will facilitate the development of more effective therapy. |
| Databáze: | OpenAIRE |
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