Transmission patterns of human enterovirus 71 to, from and among European countries, 2003 to 2013
| Autor: | Agnes Farkas, Jean-Luc Bailly, Christine Archimbaud, Chervin Hassel, Hartwig P. Huemer, Isabelle Schuffenecker, Audrey Mirand, Alexander N. Lukashev, Cécile Henquell, Sabine Diedrich, Elena Terletskaia-Ladwig, Hélène Peigue-Lafeuille |
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| Přispěvatelé: | Laboratoire Microorganismes : Génome et Environnement (LMGE), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Hospices Civils de Lyon (HCL), Epidémiologie et pathogénie des infections à entérovirus (EPIE), Université d'Auvergne - Clermont-Ferrand I (UdA) |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Genes
Viral Genotype Epidemiology Molecular Sequence Data Iceland Zoology Disease Virus Disease Outbreaks 03 medical and health sciences [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Virology Enterovirus 71 Enterovirus Infections media_common.cataloged_instance Humans European Union European union Phylogeny 030304 developmental biology media_common 0303 health sciences Molecular Epidemiology [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases Polymorphism Genetic Phylogenetic tree biology Molecular epidemiology Geography 030306 microbiology Transmission (medicine) Norway Public Health Environmental and Occupational Health Outbreak Bayes Theorem biology.organism_classification 3. Good health Enterovirus A Human Europe [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology RNA Viral [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie Sentinel Surveillance Switzerland |
| Zdroj: | Eurosurveillance Eurosurveillance, European Centre for Disease Prevention and Control, 2015, 20 (34), ⟨10.2807/1560-7917.es.2015.20.34.30005⟩ Eurosurveillance, 2015, 20 (34), ⟨10.2807/1560-7917.es.2015.20.34.30005⟩ |
| ISSN: | 1560-7917 1025-496X |
| Popis: | International audience; Enterovirus 71 (EV-71) is involved in epidemics of hand, foot, and mouth disease (HFMD) and has been reported to occur with severe neurological complications in eastern and southeast Asia. In other geographical areas, the transmission of this virus is poorly understood. We used large sequence datasets (of the gene encoding the viral protein 1, VP1) and a Bayesian phylogenetic approach to compare the molecular epidemiology and geographical spread patterns of EV-71 subgenogroups B4, B5, C1, C2, and C4 in Europe relative to other parts of the world. For the study, European countries considered were European Union (EU) Member States and Iceland, Norway and Switzerland. Viruses of the B4, B5, and C4 subgenogroups circulate mainly in eastern and southeast Asia. In Europe sporadic introductions of these subgenogroups are observed, however C1 and C2 viruses predominate. The phylogenies showed evidence of multiple events of spread involving C1 and C2 viruses within Europe since the mid-1990s. Two waves of sporadic C2 infections also occurred in 2010 and 2013. The 2007 Dutch outbreak caused by C2 and the occurrence of B5 and C4 infections in the EU between 2004 and 2013 arose while the circulation of C1 viruses was low. A transmission chain involving a C4 virus was traced from Japan to the EU and then further to Canada between 2001 and 2006. Recent events whereby spread of viruses have occurred from, to, and within Europe appear to be involved in the long term survival of EV-71, highlighting the need for enhanced surveillance of this virus. |
| Databáze: | OpenAIRE |
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