(CF3CO)2O/CF3SO3H-mediated synthesis of 1,3-diketones from carboxylic acids and aromatic ketones
| Autor: | Jung Keun Kim, Vladimir Kovalev, Elvira Shokova, Victor A. Tafeenko |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
heterocycles
triflic acid Claisen condensation Chemistry Organic Chemistry Aromatic ketones Trifluoroacetic acid anhydride trifluoroacetic acid anhydride Full Research Paper lcsh:QD241-441 Acylation 1 3-diketones chemistry.chemical_compound lcsh:Organic chemistry Organic chemistry lcsh:Q lcsh:Science Triflic acid |
| Zdroj: | Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 2270-2278 (2014) Beilstein Journal of Organic Chemistry |
| ISSN: | 1860-5397 |
| DOI: | 10.3762/bjoc.10.236 |
| Popis: | A very simple and convenient reaction for 1,3-diketone preparation from carboxylic acids and aromatic ketones in TFAA/TfOH system is described. When the β-phenylpropionic acids were used as starting materials, they initially gave 1-indanones and then underwent further acylation with the formation of 2-(β-phenylpropionyl)-1-indanones as the main reaction products. In addition, the application of the proposed protocol allowed for the synthesis of selected polysubstituted pyrazoles in a one-pot procedure directly from acids and ketones. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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