Women's preferences for the levonorgestrel intrauterine system versus endometrial ablation for heavy menstrual bleeding
| Autor: | Malou C. Herman, Lotte van den Wijngaard, Madelon van Wely, Pleun Beelen, Nathalie J J Claassen, Jan Willem van der Steeg, Peggy M.A.J. Geomini, Marlies Y. Bongers, Marian J van den Brink |
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| Přispěvatelé: | Promovendi ODB, Obstetrie & Gynaecologie, RS: GROW - R4 - Reproductive and Perinatal Medicine, MUMC+: MA Medische Staf Obstetrie Gynaecologie (9), Obstetrics and Gynaecology, Graduate School, APH - Personalized Medicine, Amsterdam Reproduction & Development (AR&D), APH - Methodology, Center for Reproductive Medicine |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment MENORRHAGIA Discrete choice experiment Levonorgestrel law.invention BALLOON ABLATION 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law MANAGEMENT Humans Medicine Outpatient clinic 030212 general & internal medicine Patient preference Endometrial ablation NOVASURE Endometrial Ablation Techniques OUTCOMES 030219 obstetrics & reproductive medicine Hysterectomy business.industry Obstetrics Heavy menstrual bleeding Intrauterine Devices Medicated Obstetrics and Gynecology Middle Aged Menstrual bleeding CONJOINT-ANALYSIS APPLICATIONS Reproductive Medicine RANDOMIZED-CONTROLLED-TRIAL HYSTERECTOMY Female 5-YEAR FOLLOW-UP HEALTH business medicine.drug Hormone Levonorgestrel intrauterine system |
| Zdroj: | European Journal of Obstetrics & Gynecology and Reproductive Biology, 228, 143-147. Elsevier European Journal of Obstetrics, Gynecology, and Reproductive Biology, 228, 143-147. ELSEVIER SCIENCE BV European journal of obstetrics, gynecology, and reproductive biology, 228, 143-147. Elsevier Ireland Ltd |
| ISSN: | 0301-2115 |
| Popis: | Objectives: Women's preferences for treatment of heavy menstrual bleeding (HMB) are important in clinical decision-making. Our aim was to investigate whether women with HMB have a preference for treatment characteristics of the levonorgestrel intrauterine system (LNG-IUS) or endometrial ablation and to assess the relative importance of these characteristics.Study Design: A discrete choice experiment was performed in general practices and gynaecology outpatient clinics in the Netherlands. Women with HMB were asked to choose between hypothetical profiles containing characteristics of LNG-IUS or endometrial ablation. Characteristics included procedure performed by gynaecologist or general practitioner; reversibility of the procedure; probability of dysmenorrhea; probability of irregular bleeding; additional use of contraception; need to repeat the procedure after five years; and treatment containing hormones. Data were analysed using panel mixed logit models. The main outcome measures were the relative importance of the characteristics and willingness to make trade-offs.Results: 165 women completed the questionnaire; 36 (22%) patients were recruited from general practices and 129 (78%) patients were recruited from gynaecology outpatient clinics. The characteristic found most important was whether a treatment contains hormones. Women preferred a treatment without hormones, a treatment with the least side effects, and no need for a repeat procedure or additional contraception. Women completing the questionnaire at the gynaecology outpatient clinic differed from women in primary care in their preference for a definitive treatment to be performed by a gynaecologist.Conclusions: Whether or not a treatment contains hormones was the most important characteristic influencing patient treatment choice for HMB. Participants preferred characteristics that were mostly related to endometrial ablation, but were willing to trade-off between characteristics. (C) 2018 Elsevier B.V. All rights reserved. |
| Databáze: | OpenAIRE |
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