Cyclin D1 and PSA act as good prognostic and clinicopathological indicators for breast cancer
| Autor: | Aiat Shaban Hemida, Nanis S Holah |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Oncology medicine.medical_specialty Clinical Biochemistry Immunology Breast Neoplasms 01 natural sciences Cyclin D1 Breast cancer Internal medicine Biomarkers Tumor Humans Immunology and Allergy Medicine Aged Retrospective Studies Aged 80 and over business.industry Carcinoma Ductal Breast 010401 analytical chemistry Cancer Middle Aged Prostate-Specific Antigen medicine.disease 0104 chemical sciences Medical Laboratory Technology Immunohistochemistry Female business Breast carcinoma |
| Zdroj: | Journal of Immunoassay and Immunochemistry. 41:28-44 |
| ISSN: | 1532-4230 1532-1819 |
| DOI: | 10.1080/15321819.2019.1677706 |
| Popis: | Breast cancer is one of the main causes of malignancies in females. Many prognostic parameters are verified but they do not give sufficient data about patients' outcome. So, we must search for new prognostic and clinicopathological parameters. This study aimed to evaluate immunohistochemical expression of cyclin D1 and PSA in breast carcinoma and their relation to prognosis. It includes 79 specimens of breast invasive duct carcinoma. Overall survival time was available for all patients. There is a statistically significant association between positive PSA expression and lower tumor stage, nodal stage and tumor grade and between negative PSA expression and presence of metastasis ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|