Esophageal carcinoma with tracheal stenosis due to tumor invasion and long survival after chemoradiotherapy
| Autor: | M. Matsuda, S. Matoba, Harushi Udagawa, Y Kinoshita, G. Watanabe, Kenji Tsutsumi, T. Sawada, S. Hukuda, Masaki Ueno, Shinji Mine, T. Hayakawa, M. Hashimoto, K. Sasaki |
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| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Esophageal Neoplasms Fistula medicine.medical_treatment Hypopharyngeal Carcinoma Carcinoma medicine Humans Combined Modality Therapy Neoplasm Invasiveness Survivors Esophagus Chemotherapy business.industry Remission Induction Gastroenterology General Medicine Middle Aged medicine.disease Tracheal Stenosis Surgery medicine.anatomical_structure business Chemoradiotherapy |
| Zdroj: | Diseases of the Esophagus. 16:261-264 |
| ISSN: | 1442-2050 1120-8694 |
| DOI: | 10.1046/j.1442-2050.2003.00340.x |
| Popis: | For patients who have esophageal carcinoma with tracheal invasion surgery is usually not indicated because operative complications are considerable and the prognosis is poor. We experienced complete regression of a large esophageal carcinoma with tracheal stenosis due to tumor invasion without tracheo-esophageal fistula. Irradiation of 68 Gy was delivered to a long T field from the neck to the lower thoracic esophagus, and was combined with chemotherapy using cisplatin and 5-fluorouracil. The tumor decreased markedly in size and the tracheal stenosis resolved. The patient has survived for 4 years, although second primary early esophageal carcinoma and hypopharyngeal carcinoma were detected 2 years after his initial chemoradiotherapy. Although the prognosis of advanced esophageal carcinoma with invasion of other organs is usually poor, the effect of chemoradiotherapy can sometimes be dramatic and a good result can be achieved in such patients. |
| Databáze: | OpenAIRE |
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