A novel rituximab administration protocol to minimize infusion-related adverse reactions in patients with B-cell lymphoma

Autor:	Daisuke Tsutsumi, Tatsuya Hayama, Katsuhiro Miura, Akihiro Uchiike, Shinya Tsuboi, Susumu Otsuka, Yoshihiro Hatta, Yukinaga Kishikawa
Rok vydání:	2021
Předmět:	Pharmacology Lymphoma B-Cell Drug-Related Side Effects and Adverse Reactions Risk Factors Incidence Humans Pharmaceutical Science Antineoplastic Agents Pharmacology (medical) Pharmacy Rituximab Toxicology
Zdroj:	International Journal of Clinical Pharmacy. 44:366-373
ISSN:	2210-7711 2210-7703
Popis:	Background Infusion-related reactions (IRRs) during rituximab administration are occasionally severe and remain problematic in oncology practice. Aim To establish a safer, risk-stratified rituximab protocol for patients with B-cell lymphoma. Method We stratified patients into low-, moderate-, and high-risk groups according to the number of risk factors for IRRs, specifically, low-grade histology and bulky tumors ( 10 cm): Then, the administrating schedule of rituximab (375 mg/m
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a542f91a29bbe2ee3dd99157ba9f6dd5 https://doi.org/10.1007/s11096-021-01348-6 Zobrazit plný text záznamu Full text from SpringerLink