Gabapentin toxicity: an important cause of altered consciousness in patients with uraemia
| Autor: | Vei-Ken Seow, Tzu-Yao Hung, Chong Cf, Chen Cc, Tzong-Luen Wang |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Cyclohexanecarboxylic Acids Gabapentin medicine.medical_treatment Renal function Critical Care and Intensive Care Medicine Article Diagnosis Differential Lethargy Level of consciousness Renal Dialysis Diabetes mellitus Humans Medicine Amines Adverse effect gamma-Aminobutyric Acid Dialysis Uremia business.industry General Medicine Middle Aged medicine.disease Surgery Anesthesia Toxicity Emergency Medicine Consciousness Disorders Anticonvulsants Female business medicine.drug |
| Zdroj: | BMJ case reports. 2009 |
| ISSN: | 1757-790X |
| Popis: | Gabapentin toxicity should be considered one of the differential diagnoses of altered consciousness in patients with compromised renal function, even after a single dose. We report a 57-year-old woman with diabetes mellitus and uraemia on regular haemodialysis who developed severe dizziness and lethargy after a single recommended dose of gabapentin for bilateral leg dysthesia. Because of progressive drowsiness and decreasing level of consciousness, one session of haemodialysis was performed and clinical recovery was dramatic. The adverse effects of gabapentin seem to vary from person to person and should be viewed with a high degree of suspicion, especially in patients taking this drug at the beginning. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|