Conditioning by a Previous Experience Impairs the Rewarding Value of a Comfort Meal
| Autor: | Adoracion Nieto, Dan M. Livovsky, Fernando Azpiroz |
|---|---|
| Přispěvatelé: | Institut Català de la Salut, [Nieto A, Azpiroz F] Servei d’Aparell Digestiu, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (Ciberehd), Instituto de Salud Carlos III, Madrid, Spain. [Livovsky DM] Servei d’Aparell Digestiu, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Digestive Diseases Institute, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel, Vall d'Hebron Barcelona Hospital Campus |
| Rok vydání: | 2023 |
| Předmět: |
Digestió
Aparell digestiu - Fisiologia Behavior and Behavior Mechanisms::Emotions [PSYCHIATRY AND PSYCHOLOGY] Nutrition and Dietetics Pavlovian conditioning aversive conditioning eating behaviour digestive sensations postprandial symptoms digestive well-being food valence Physiological Phenomena::Diet Food and Nutrition::Nutritional Physiological Phenomena::Digestion [PHENOMENA AND PROCESSES] Emocions conducta y mecanismos de la conducta::emociones [PSIQUIATRÍA Y PSICOLOGÍA] Digestive System and Oral Physiological Phenomena::Digestive System Physiological Phenomena::Postprandial Period [PHENOMENA AND PROCESSES] fenómenos fisiológicos orales y del sistema digestivo::fenómenos fisiológicos del sistema digestivo::período posprandial [FENÓMENOS Y PROCESOS] fenómenos fisiológicos::dieta alimentación y nutrición::fenómenos fisiológicos nutricionales::digestión [FENÓMENOS Y PROCESOS] Food Science |
| Zdroj: | Nutrients; Volume 15; Issue 10; Pages: 2247 Scientia |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu15102247 |
| Popis: | Pavlovian conditioning; Digestive well-being; Eating behaviour Condicionamiento pavloviano; Bienestar digestivo; Conducta alimentaria Condicionament pavlovià; Benestar digestiu; Conducta alimentària Background. Meal ingestion induces a postprandial experience that involves homeostatic and hedonic sensations. Our aim was to determine the effect of aversive conditioning on the postprandial reward of a comfort meal. Methods: A sham-controlled, randomised, parallel, single-blind study was performed on 12 healthy women (6 per group). A comfort meal was tested before and after coupling the meal with an aversive sensation (conditioning intervention), induced by infusion of lipids via a thin naso-duodenal catheter; in the pre- and post-conditioning tests and in the control group, a sham infusion was performed. Participants were instructed that two recipes of a tasty humus would be tested; however, the same meal was administered with a colour additive in the conditioning and post-conditioning tests. Digestive well-being (primary outcome) was measured every 10 min before and 60 min after ingestion using graded scales. Results: In the aversive conditioning group, the comfort meal in the pre-conditioning test induced a pleasant postprandial experience, which was significantly lower in the post-conditioning test; the effect of aversive conditioning (change from pre- to post-conditioning) was significant as compared to sham conditioning in the control group, which showed no differences between study days. Conclusion: The hedonic postprandial response to a comfort meal in healthy women is impaired by aversive conditioning. ClinicalTrials.gov ID: NCT04938934. The present study was supported in part by the Ministerio de Ciencia e Innovación (Agencia Estatal de Investigación, PID2021-122295OB-I00). Ciberehd is funded by the Instituto de Salud Carlos III. D.M.L received support from the Israeli Medical Association and from the Israel Gastroenterological Association. |
| Databáze: | OpenAIRE |
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