Patterns of prospective and retrospective memory impairment in preclinical Alzheimer's disease
| Autor: | Lars Bäckman, Åsa Livner, Sari Jones |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Prom Neuropsychological Tests Physical medicine and rehabilitation Alzheimer Disease Retrospective memory Prospective memory medicine Humans Dementia Memory disorder Episodic memory Aged Retrospective Studies Aged 80 and over Memory Disorders Cognitive disorder Recognition Psychology medicine.disease female genital diseases and pregnancy complications Neuropsychology and Physiological Psychology Case-Control Studies Mental Recall Female Alzheimer's disease Mental Status Schedule Psychology Neuroscience |
| Zdroj: | Neuropsychology. 20:144-152 |
| ISSN: | 1931-1559 0894-4105 |
| DOI: | 10.1037/0894-4105.20.2.144 |
| Popis: | Forty-six preclinical Alzheimer's disease (AD) participants and 188 nondemented control persons from the Kungsholmen Project (L. Bäckman et al., 2004) were compared on prospective memory (ProM) and retrospective memory (RetM) tasks 3 years before dementia diagnosis. The preclinical AD participants showed deficits in both ProM and RetM. Most interestingly, logistic regression analyses revealed that ProM made an independent contribution to the prediction of AD over and above that of RetM. This finding suggests that ProM and RetM tap partly different cognitive operations. Furthermore, within the ProM task, both the retrospective and prospective components were similarly impaired in preclinical AD. Within RetM, the preclinical AD participants were impaired on indices of encoding, storage (forgetting), and retrieval of information. Hence, the findings indicate a rather global episodic memory impairment in preclinical AD that cuts across type of memory assessed (ProM and RetM) as well as across different components of both the ProM and RetM tasks. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|