Effect of a liberal versus a restrictive pre-donation blood pressure policy on whole-blood donor adverse reactions
| Autor: | Marco Sandri, Massimo Daves, Rudolf Hueber, Francesco Maniscalco, Ivo Gentilini, Ahmad Al-Khaffaf, Ugo Salvadori, Karl Egger, Cinzia Vecchiato, Christina Troi, Franz Ploner, Roberto Cemin, Astrid Griessmair, Gottfried Kuehebacher |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Hemovigilance medicine.medical_specialty Adolescent Systole Diastole Blood Donors Blood Pressure 030204 cardiovascular system & hematology Logistic regression Donor Selection 03 medical and health sciences Young Adult 0302 clinical medicine Risk Factors Syncope Vasovagal Medicine Humans Blood Transfusion Aged Retrospective Studies Univariate analysis business.industry Obstetrics Incidence (epidemiology) Incidence Hematology General Medicine Middle Aged Blood pressure Logistic Models Italy Donation Whole blood donor Blood Banks Female Hypotension business 030215 immunology |
| Zdroj: | Vox sanguinis. 114(4) |
| ISSN: | 1423-0410 |
| Popis: | BACKGROUND AND OBJECTIVES The role of pre-donation blood pressure (BP) as independent contributor to post-donation vasovagal reactions (VVRs) is still debated. Differences between a liberal (i.e., inclusion of hypotensive donors) and a restrictive policy (i.e., not accepting hypotensive donors) should be investigated. This study aims to investigate the consequences of a liberal policy in development of VVRs after whole-blood donations. MATERIALS AND METHODS We compared the incidence of VVRs between 2015 (restrictive policy) and 2016 (liberal policy) and the associated risk factors. We evaluated respectively 22 789 vs. 21 676 blood donations obtained from 18 001 blood donors (12 501 donated in both years). RESULTS Comparing the results we obtained between 2015 and 2016, donations showed an overlap of the cohorts. Two hundred fifteen VVRs (incidence rate 0·48%) were observed, 104 (0·46%) of which in 2015, and 111 (0·51%) in 2016. A preliminary univariate analysis showed that donors with systolic BP |
| Databáze: | OpenAIRE |
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