Can constant light exposure affect the thyroid gland in prepubertal male albino rats? Histological and ultrastructural study
| Autor: | F. A. Abdel Gawad, S. F. Arsanyos, Ehab A. A. El-Shaarawy, T I Abd El-Galil, G N Awes |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Histology Light Thyroid Gland Muscle hypertrophy 03 medical and health sciences Internal medicine Follicular phase medicine Animals Sexual Maturation Constant light 0303 health sciences business.industry Thyroid Hyperplasia medicine.disease Rats Light intensity medicine.anatomical_structure Endocrinology 030301 anatomy & morphology Ultrastructure Anatomy Thyroid function business |
| Zdroj: | Folia morphologica. 78(2) |
| ISSN: | 1644-3284 |
| Popis: | Background: Through scientific literature, there is evidence that light affects thyroid function in human, mice and rabbits. Constant light and sleep deprivation is also used as a form of human torture, as it has impact on cognitive performances. The present work was conducted to study the effect of constant light for short and long periods on the thyroid gland in the prepubertal male albino rats. Materials and methods: A total of 30 prepubertal male albino rats were used. The rats separated into three groups: group I (control); group II were those rats put under steady encompassing light (24 h/day, light intensity of 600 lux) for 4 weeks; and group III were the rats maintained in constant light for 3 months. The rat thyroid gland was subjected to histological and ultrastructural examination. Results: The rats exposed to light for long durations showed disturbed architecture; the follicles exhibited back to back arrangement (signs of hypertrophy with hyperplasia), lined by multiple layers of follicular cells or were lined by vacuolated cells. Few thyroid follicles exhibited cystic hyperplasia. Congested blood capillaries were demonstrated between the follicles. Conclusions: It can be concluded that the short-term exposure to constant light for 1 month had no apparent effect on thyroid gland tissues while longer exposure to light for 3 months had detrimental effects on the thyroid gland structure of male albino rats. |
| Databáze: | OpenAIRE |
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