Aging patterns of Japanese auditory semantic processing: an fMRI study
| Autor: | Hengshuang Liu (柳恒爽), Makoto Miyakoshi, Toshiharu Nakai, Shen-Hsing Annabel Chen |
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| Přispěvatelé: | School of Social Sciences, Lee Kong Chian School of Medicine (LKCMedicine), Centre for Research and Development in Learning (CRADLE) |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Aging
Life span Compensation (psychology) Stereotype (UML) Experimental and Cognitive Psychology Magnetic Resonance Imaging Crunch Semantics Psychiatry and Mental health Neuropsychology and Physiological Psychology Japan Psychology [Social sciences] Listening comprehension Auditory Perception Humans Semantic memory Dedifferentiation Geriatrics and Gerontology Cognitive decline Psychology Compensation Aged Cognitive psychology |
| Popis: | The efficacy of listening comprehension is presumably sustained over the life span, contradicting the stereotype of universal cognitive decline. It is thus worth investigating whether and how the preserved auditory semantic function is supported by affected or unaffected neural mechanism with age. To investigate this issue, 22 younger and 21 older Japanese adults were imaged in a 3 Tesla MRI scanner while performing an auditory semantic-tone task. Results showed that (a) relative to younger adults, older participants had preserved accuracy and slowed responses, underpinned by weakened interconnectivity and largely unchanged activation and laterality; (b) older adults with superior performance developed increased regional left-lateralization and stronger interregional connectivity within the domain-general networks; (c) these age-related or performance-related cortical reorganizations were largely consistent with neurocognitive aging models that were supported by age-sensitive cognitive domains, suggesting that these models might also be accountable for relatively age-intact cognitive functions such as auditory semantic processing. Nanyang Technological University This work was supported by the Japan Society for the Promotion of Science (JSPS) under Grants-in-Aid for Scientific Research (KAKENHI #15H03104 and 19H04025); and a funding source for NTU-SUG from Nanyang Technological University. The second author was supported by a generous gift of Swartz Foundation (Old Field, New York). |
| Databáze: | OpenAIRE |
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