The regenerative effects of electromagnetic field on spinal cord injury
| Autor: | Ishaq Syed, Christina L Ross, Thomas L. Smith, Benjamin S. Harrison |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Magnetic Field Therapy Biophysics Medicine (miscellaneous) 03 medical and health sciences Osteoclast medicine Animals Humans Viability assay Spinal cord injury Spinal Cord Injuries Neuroinflammation Clinical Trials as Topic business.industry Mesenchymal stem cell General Medicine Anatomy medicine.disease Spinal cord Chondrogenesis Nerve Regeneration Cell biology 030104 developmental biology medicine.anatomical_structure Stem cell business |
| Zdroj: | Electromagnetic Biology and Medicine. :1-14 |
| ISSN: | 1536-8386 1536-8378 |
| Popis: | Traumatic spinal cord injury (SCI) is typically the result of direct mechanical impact to the spine, leading to fracture and/or dislocation of the vertebrae along with damage to the surrounding soft tissues. Injury to the spinal cord results in disruption of axonal transmission of signals. This primary trauma causes secondary injuries that produce immunological responses such as neuroinflammation, which perpetuates neurodegeneration and cytotoxicity within the injured spinal cord. To date there is no FDA-approved pharmacological agent to prevent the development of secondary SCI and induce regenerative processes aimed at healing the spinal cord and restoring neurological function. An alternative method to electrically activate spinal circuits is the application of a noninvasive electromagnetic field (EMF) over intact vertebrae. The EMF method of modulating molecular signaling of inflammatory cells emitted in the extra-low frequency range of |
| Databáze: | OpenAIRE |
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