Influenza A infection in young infants
| Autor: | Floris Levy-Khademi, Eitan Kerem, David Rekhtman, Isaiah D. Wexler, Dana G. Wolf, Diana Averbuch |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Fever Respiratory Syncytial Virus Infections Virus Young infants Sepsis Influenza Human medicine Humans Respiratory system Mild disease Retrospective Studies Family Health Respiratory distress business.industry Infant Newborn virus diseases Infant Influenza a Length of Stay medicine.disease Prognosis Hospitalization medicine.anatomical_structure Influenza A virus Pediatrics Perinatology and Child Health Immunology Female business Respiratory Insufficiency Respiratory tract |
| Zdroj: | Archives of disease in childhood. 96(11) |
| ISSN: | 1468-2044 |
| Popis: | Objective To determine the clinical characteristics of infants ≤2 months old hospitalised with influenza A. Study design The study was a retrospective analysis of infants ≤2 months old hospitalised with fever, respiratory distress and/or sepsis. Clinical signs, laboratory values, hospital duration and outcome were compared between children with influenza A and other viruses. Results The charts of 268 infants were reviewed. 29 (11%) children had laboratory-confirmed influenza A infection. Unique features associated with influenza infection included the high number presenting with fever (97%) and a history of exposure to family members with a flu-like illness (69%). A significantly lower rate of respiratory distress was observed in the influenza group compared with respiratory syncytial virus (RSV) (24% vs 89%, p≤0.001). Median duration of hospitalisation for influenza was shorter than RSV (4 days vs 6 days, p Conclusions In young infants, influenza A is a relatively mild disease compared to RSV and is primarily associated with upper respiratory tract manifestations. |
| Databáze: | OpenAIRE |
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