Unexpected pathogen presenting with purulent meningitis
| Autor: | Carlos A. Hartmann, Kara Asbury, Holenarasipur R. Vikram, Jamie Bering |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Purulent meningitis 030106 microbiology Meningitis Bacterial Diagnosis Differential 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Acute onset Anti-Infective Agents Piperidines Medicine Humans Intensive care medicine Pathogen Aged Lymphocytic leukaemia biology business.industry Adenine General Medicine Capnocytophaga canimorsus biology.organism_classification medicine.disease Reminder of Important Clinical Lesson Leukemia Lymphoid Pyrimidines chemistry Capnocytophaga sp Ibrutinib Pyrazoles business Gram-Negative Bacterial Infections Meningitis Capnocytophaga 030217 neurology & neurosurgery |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| Popis: | Herein we report a case of a 67-year-old man with chronic lymphocytic leukaemia who developed acute onset of fever and altered mental status while receiving ibrutinib therapy. He was eventually found to have Capnocytophaga canimorsus meningitis. Timely diagnosis and appropriate antimicrobial therapy was associated with a favourable outcome. We describe challenges associated with appropriate identification of, and briefly review infections caused by Capnocytophaga sp. To our knowledge, this is the first case of invasive C. canimorsus infection in the setting of ibrutinib therapy, and adds to the growing list of serious infections that have been associated with this agent. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|