Acid-base state of the preterm infant and the formulation of intravenous feeding solutions
| Autor: | Mitch Blair, P D Mayne, P MacMahon, C Pope, I Z Kovar |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
Parenteral Nutrition Potassium Compounds Sodium chemistry.chemical_element Urine Acid–base homeostasis Calcium Buffers Phosphates chemistry.chemical_compound Animal science medicine Hydroxides Humans Sorbitol Acid-Base Equilibrium business.industry Phosphorus Infant Newborn Metabolic acidosis Hydrogen-Ion Concentration Phosphate medicine.disease Sodium Compounds Surgery chemistry Pediatrics Perinatology and Child Health Potassium Infant Food Acid–base reaction business Infant Premature Research Article |
| Zdroj: | Archives of disease in childhood. 65(4 Spec) |
| ISSN: | 1468-2044 |
| Popis: | An acidic intravenous source of phosphorus (Addiphos) was compared with dipotassium hydrogen phosphate in 25 preterm infants to study acid-base state. Eight infants were given either Addiphos or dipotassium hydrogen phosphate alternately for 48 hour periods and similar amounts of calcium and phosphorus were delivered. There were no significant differences in calcium and phosphorus intake, calcium and phosphate plasma concentrations, or acid-base state between study periods on the two solutions. Seventeen infants were given the two solutions alternately for 72 hour periods; Addiphos was used to increase the amounts of calcium and phosphorus being delivered. Calcium and phosphorus intake was decreased on dipotassium hydrogen phosphate, but Addiphos significantly increased calcium and phosphorus intake and plasma calcium and phosphate concentrations. It also lowered the pH of the urine and raised the titratable acidity. Acid-base state, however, was not significantly different. It is therefore possible to increase intake of calcium and phosphorus in preterm infants without causing a significant metabolic acidosis. |
| Databáze: | OpenAIRE |
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