Differences in pulmonary nodular consolidation and pulmonary cavity among drug-sensitive, rifampicin-resistant and multi-drug resistant tuberculosis patients: a computerized tomography study with history length matched cases
| Autor: | Qi-Sheng, Song, Cun-Jing, Zheng, Kun-Peng, Wang, Xi-Ling, Huang, Michael, Tartakovsky, Yì Xiáng J, Wáng |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Thoracic Disease. 14:2522-2531 |
| ISSN: | 2077-6624 2072-1439 |
| DOI: | 10.21037/jtd-22-145 |
| Popis: | There have been concerns that literature described radiological feature differences between drug-sensitive pulmonary tuberculosis (DS-PTB) and multidrug-resistant (MDR)-PTB were confounded by that MDR-PTB cases tend to have a longer history. Using history length matched DS-PTB and MDR-PTB cases from a well-defined urban region in Dalian, we retrospectively analysed the CT feature differences of these paired cases with a focus on pulmonary nodular (PN) consolidation and pulmonary cavity (PC).There were 33 consecutive MDR-PTB cases [inclusive of rifampicin-resistant (RR) cases, 27 males and 6 females, mean age: 49.2 years], with 19 cases had a history of1 month and 8 and 6 cases had a history of 1-6 and6 months respectively. To pair the MDR-PTB cases with history length, matched 33 cases of DS-PTB patients (21 males and 12 females, mean age: 56.5 years) were included. All patients were new PTB without HIV infection. The first CT exams prior to treatment were analysed.Compared with DS cases, MDR cases had a much higher prevalence of PN (75.76%MDR-TB is likely intrinsically more invasive than DS-TB. Multiple PN and Multiple PC are promising signs for the suspicion of MDR-PTB on chest imaging. |
| Databáze: | OpenAIRE |
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